Leucovorin: Potential Adverse Events and Precautions
Understanding Leucovorin's Side Effects
Leucovorin, also known as folinic acid, is a medication commonly used to treat folate deficiency and certain types of cancer. While generally well-tolerated, leucovorin can cause certain adverse events, particularly when used alone or in combination with other medications.
Allergic Reactions
Rarely, leucovorin can cause allergic reactions, including sensitization. If you experience symptoms such as hives, swelling, or difficulty breathing, seek immediate medical attention.
Side Effects When Used with Fluorouracil
When leucovorin is used with fluorouracil, an antineoplastic agent used to treat cancer, it can enhance the drug's effects and potentially lead to increased toxicity. Common side effects include nausea, vomiting, diarrhea, and bone marrow suppression.
Special Precautions
It is important to note that the dosage of leucovorin can vary depending on the individual and the purpose of the medication. It is essential to follow your doctor's instructions carefully and avoid taking more than the prescribed amount.
Before using leucovorin, inform your doctor if you have any allergies, liver disease, or kidney disease. Additionally, pregnant or breastfeeding women should consult their healthcare provider before taking leucovorin.
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